Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | BCR | P11274 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174619 | 0.84 | PKM (0.40) | PKMABL1BCRNPY5RHTR6 | |
| SCHEMBL31006834 | 0.80 | CCNB2 (0.42) | ABL1BCRGRM4ALDH1A1BTK | |
| SCHEMBL16655014 | 0.75 | CA12 (0.51) | ABL1BCRHTR6ALDH1A1 | |
| SCHEMBL30886775 | 0.75 | CA12 (0.51) | ABL1BCRHTR6ALDH1A1 | |
| SCHEMBL29174604 | 0.74 | MAPT (0.50) | PKMABL1BCRALDH1A1CYP2C19 | |
| SCHEMBL30725455 | 0.74 | MAPT (0.50) | PKMABL1BCRALDH1A1CYP2C19 | |
| SCHEMBL29174594 | 0.72 | ALDH1A1 (0.38) | PKMABL1BCRHTR6GRM4 | |
| SCHEMBL30725525 | 0.72 | ALDH1A1 (0.38) | PKMABL1BCRHTR6GRM4 | |
| SCHEMBL28195638 | 0.72 | PKM (0.56) | PKMNPY5RHTR6ALDH1A1TUBB4A | |
| SCHEMBL30444276 | 0.72 | KDM4E (0.55) | PKMALDH1A1BTKCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |