Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | SMO | Q99835 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174594 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2ABL1 | |
| SCHEMBL31006834 | 0.80 | CCNB2 (0.42) | ALDH1A1MAPTABL1BCRKMT2A | |
| SCHEMBL29174604 | 0.78 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2ABL1BCR | |
| SCHEMBL30725455 | 0.78 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2ABL1BCR | |
| SCHEMBL30725488 | 0.75 | KMT2A (0.44) | ALDH1A1MAPTSMN1; SMN2ABL1BCR | |
| SCHEMBL29174582 | 0.75 | KMT2A (0.44) | ALDH1A1MAPTSMN1; SMN2ABL1BCR | |
| SCHEMBL29174697 | 0.72 | PKM (0.44) | ALDH1A1ABL1BCRGRM4HTR6 | |
| SCHEMBL6039811 | 0.72 | HTR6 (0.56) | DRD2HTR6HTR2AHTR7 | |
| SCHEMBL29429815 | 0.72 | HTR6 (0.56) | DRD2HTR6HTR2AHTR7 | |
| SCHEMBL16962210 | 0.72 | HTR6 (0.43) | ALDH1A1LMNASMN1; SMN2ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |