Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | YWHAG | P61981 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811722 | 1.00 | MKNK1 (0.44) | MKNK1MKNK2CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL3343696 | 0.74 | IP6K1 (0.55) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30711736 | 0.72 | PARP1 (0.53) | MKNK1MKNK2SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL17382227 | 0.72 | PARP1 (0.53) | MKNK1MKNK2SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL30811705 | 0.71 | CHRNB2 (0.49) | CHRNB2CHRNA4KDM4EMAPT | |
| SCHEMBL20998610 | 0.71 | BTK (0.46) | MKNK1MKNK2NPC1SYKRAB9A | |
| SCHEMBL24364823 | 0.71 | NNMT (0.43) | KDM4EMEN1KMT2APARP1 | |
| SCHEMBL19145095 | 0.71 | CHRNB2 (0.51) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL28617172 | 0.71 | LMNA (0.44) | SMN1; SMN2KDM4EKMT2APARP1 | |
| SCHEMBL31652322 | 0.70 | IP6K1 (0.50) | KDM4EMEN1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720533-A | MetTL3 inhibitor compound and pharmaceutical composition and application thereof | 北京华益健康药物研究中心 | 2024-03-19 | — | — | CN | disclosed |