Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915269 | 0.92 | CHRNA7 (0.42) | PTGS2MGLLCHRNA7 | |
| SCHEMBL2910138 | 0.90 | GPR119 (0.49) | PTGS2CFTRGPR119 | |
| SCHEMBL2911608 | 0.81 | MGLL (0.46) | PTGS2MGLLCFTRCCKAR | |
| SCHEMBL2915792 | 0.81 | MGLL (0.53) | PTGS2MGLLPTGS1EPHX2CCKAR | |
| SCHEMBL2921251 | 0.80 | MGLL (0.45) | PTGS2MGLLCFTRCCKAR | |
| SCHEMBL2918291 | 0.80 | HPGD (0.46) | PTGS2MGLLCHRNA7CFTR | |
| SCHEMBL2915598 | 0.79 | MALT1 (0.42) | PTGS2MGLLCHRNA7CCKAR | |
| SCHEMBL2916599 | 0.78 | MGLL (0.43) | MGLLCFTRCCKAR | |
| SCHEMBL2918775 | 0.78 | PTGS2 (0.52) | PTGS2MGLLCCKAR | |
| SCHEMBL2920392 | 0.78 | MGLL (0.42) | PTGS2MGLLCFTRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |