SCHEMBL291771

SCHEMBL291771

CCCCCCCCCc1ccccc1/C=C/C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 6/20 0.54
PTGER2 P43116 6/20 0.54
PTGER4 P35408 5/20 0.54
BID P55957 3/20 0.52
MCL1 Q07820 3/20 0.52
BCL2L1 Q07817 2/20 0.52
BAK1 Q16611 2/20 0.52
KAT8 Q9H7Z6 2/20 0.52
PPARA Q07869 2/20 0.52
SAE1 Q9UBE0 2/20 0.52
PPARG P37231 1/20 0.52
EP300 Q09472 1/20 0.52
KAT2A Q92830 1/20 0.52
KAT2B Q92831 1/20 0.52
KAT5 Q92993 1/20 0.52
TBXA2R P21731 2/20 0.50
PTGDR Q13258 2/20 0.50
MMP2 P08253 2/20 0.49
F7 P08709 2/20 0.49
F3 P13726 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684323 1.00 PTGER3 (0.54) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL6437827 1.00 PTGER3 (0.54) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL489896 1.00 PTGER3 (0.54) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL3250731 1.00 PTGER3 (0.54) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL2356096 1.00 PTGER3 (0.54) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL16339260 0.98 PTGER3 (0.55) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL16339259 0.98 PTGER3 (0.55) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL8702148 0.94 PTGER3 (0.56) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL7530108 0.94 PTGER3 (0.56) PTGER3PTGER2PTGER4BIDMCL1
SCHEMBL1542126 0.94 PTGER3 (0.56) PTGER3PTGER2PTGER4BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531668-B1 MICROENCAPSULATED AGROCHEMICAL COMPOSITION SYNGENTA LTD (GB) 2009-06-17 EP claimed
US-20170367973-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT MALVERN COSMECEUTICS LIMITED (GB) 2017-12-28 US disclosed
US-20160022569-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT MALVERN COSMECEUTICS LIMITED (GB) 2016-01-28 US disclosed
EP-2428200-A2 Novel compositions Malvern Cosmeceutics Limited (GB) 2012-03-14 EP disclosed
US-20100196290-A1 COMPOSITIONS COMPRISING BETULONIC ACID VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 2010-08-05 US disclosed
US-20100062067-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT MALVERN COSMECEUTICS LIMITED (GB) 2010-03-11 US disclosed
EP-2037872-A2 COMPOSITIONS COMPRISING BETULONIC ACID Valtion Teknillinen Tutkimuskeskus (FI) 2009-03-25 EP disclosed
US-7402300-B2 Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds L'OREAL (FR) 2008-07-22 US disclosed
WO-2007141392-A2 COMPOSITIONS COMPRISING BETULONIC ACID VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 2007-12-13 WO disclosed
WO-2007064886-A2 SPRAY BOOTH AND METHOD FOR COATING THE HUMAN BODY WITH SUNSCREEN OR THE LIKE MCGUIRE KENT (US) 2007-06-07 WO disclosed
US-20070125798-A1 Spray booth and method for coating the human body with sunscreen or the like MCGUIRE KENT 2007-06-07 US disclosed
US-20060177393-A1 Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds L'OREAL (FR) 2006-08-10 US disclosed
EP-1671675-A1 Sun protection composition comprising at least a lipophilic uv filter and a hydroxyalkyl urea derivative L'OREAL (FR) 2006-06-21 EP disclosed
EP-1117641-B1 INDOLIN DERIVATIVES AS SUN PROTECTION AGENTS CIBA SC HOLDING AG (CH) 2004-03-24 EP disclosed
EP-1123950-B1 Method for preventing settlement of aquatic fouling organisms NIPPON PAINT CO LTD (JP) 2003-11-26 EP disclosed
EP-1123950-A1 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 2001-08-16 EP disclosed
EP-0702065-A2 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 1996-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170367973-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT APOB, CLTB, ABCB4 PTGER3 3967/4885PTGER2 4209/4885PTGER4 3919/4885
US-20060177393-A1 Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds CUTA, S100A11, KRT18 PTGER3 2280/4885PTGER2 3101/4885PTGER4 1576/4885
US-20160022569-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT APOB, CLTB, ABCB4 PTGER3 3967/4885PTGER2 4209/4885PTGER4 3919/4885
US-20100196290-A1 COMPOSITIONS COMPRISING BETULONIC ACID BET1, PGGT1B, RABGGTB PTGER3 2286/4885PTGER2 2954/4885PTGER4 2917/4885
US-20100062067-A1 COMPOSITIONS COMPRISING MACROMOLECULAR ASSEMBLIES OF LIPID AND SURFACTANT CLTB, APOB, ABCB4 PTGER3 3264/4885PTGER2 3565/4885PTGER4 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.