Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178422 | 0.83 | MTNR1A (0.50) | HTR6MAPTHTR2A | |
| SCHEMBL11618111 | 0.78 | SOS1 (0.39) | GPR84AVPR1ASLC6A4SOS1 | |
| SCHEMBL12244120 | 0.77 | HTR6 (0.68) | GPR84HTR6HTR2AHTR2C | |
| SCHEMBL17956261 | 0.75 | GPR84 (0.54) | GPR84SLC6A4LMNAMAPTPKM | |
| SCHEMBL840736 | 0.75 | GPR84 (0.65) | GPR84SLC6A4LMNAMAPTPKM | |
| SCHEMBL29623480 | 0.75 | GPR84 (0.65) | GPR84SLC6A4LMNAMAPTPKM | |
| SCHEMBL29178357 | 0.74 | CYP2C19 (0.45) | GPR84AVPR1ASLC6A4LMNAMAPT | |
| SCHEMBL24815224 | 0.74 | GPR84 (0.63) | GPR84SLC6A4LMNAMAPTPKM | |
| SCHEMBL30396876 | 0.74 | GPR84 (0.63) | GPR84SLC6A4LMNAMAPTPKM | |
| SCHEMBL5228493 | 0.74 | GPR84 (0.63) | GPR84SLC6A4LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |