Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 8/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.32 |
| ▸ | ERBB3 | P21860 | 8/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 8/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15612939 | 0.74 | DYRK1A (0.53) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL29178671 | 0.71 | DYRK1A (0.46) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL13768011 | 0.68 | KDM4E (0.49) | DYRK1AMKNK2IRAK4EGFRERBB2 | |
| SCHEMBL16432196 | 0.67 | TRPA1 (0.55) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL23158613 | 0.64 | DYRK1A (0.64) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL8223 | 0.64 | DYRK1A (1.00) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL3386908 | 0.64 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL29702869 | 0.64 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL1056424 | 0.64 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL13186164 | 0.64 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |