Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 11/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 11/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 11/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768011 | 0.74 | KDM4E (0.49) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL15612939 | 0.74 | DYRK1A (0.53) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL4001800 | 0.73 | CDC7 (0.60) | DYRK1AMAP3K7TAB1EGFRERBB2 | |
| SCHEMBL29178674 | 0.71 | DYRK1A (0.46) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL30539061 | 0.70 | RAB9A (0.57) | EGFR | |
| SCHEMBL8325550 | 0.70 | HTR6 (0.41) | — | |
| SCHEMBL10569355 | 0.67 | ALDH1A1 (0.45) | MAP3K7TAB1CYP17A1 | |
| SCHEMBL29418928 | 0.67 | EGFR (0.42) | EGFRCYP17A1 | |
| SCHEMBL16809892 | 0.65 | DYRK1A (0.55) | DYRK1AEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL3575456 | 0.64 | TRPA1 (0.51) | DYRK1AEGFRERBB2ERBB3ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |