Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733721 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL16481265 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL3480424 | 0.79 | TDP1 (0.37) | SMN1; SMN2MAPTRAB9ALMNATSHR | |
| SCHEMBL21835728 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL27454977 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL6466375 | 0.72 | DRD1 (0.37) | MAPTNPC1RAB9ALMNAALOX15 | |
| SCHEMBL9860015 | 0.71 | SRD5A2 (0.45) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL30294336 | 0.71 | MAPT (0.54) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL838442 | 0.71 | MAPT (0.54) | SMN1; SMN2HAO1MAPTNPC1RAB9A | |
| SCHEMBL28384768 | 0.71 | LDHA (0.47) | MAPTRAB9ALMNAALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597341-A | Sulfonamide derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |