Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294336 | 1.00 | MAPT (0.54) | MAPTNPC1RAB9AHAO1MEN1 | |
| SCHEMBL1257369 | 0.98 | MAPT (0.53) | MAPTNPC1RAB9AHAO1MEN1 | |
| SCHEMBL3527439 | 0.83 | CA12 (0.48) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29427042 | 0.83 | CA12 (0.48) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13614304 | 0.83 | MAPT (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1134723 | 0.82 | CA1 (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30250475 | 0.82 | CA1 (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7465577 | 0.78 | LTA4H (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6449465 | 0.78 | CA1 (0.48) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25405284 | 0.77 | SMN1; SMN2 (0.53) | MAPTNPC1RAB9AHAO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736102-B | Synthesis method of 4-bromo-3-methylanisole | 山东默锐科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-116178182-B | Preparation method of 2-methyl-4-methoxy diphenylamine | 山东默锐科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-108794307-B | Micro-reaction system and method for synthesizing 4-bromo-3-methylanisole by solvent method | 山东道可化学有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-114736102-A | Synthesis method of 4-bromo-3-methylanisole | 山东默锐科技有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-109053391-B | Micro-reaction system and method for synthesizing 4-bromo-3-methylanisole by two-phase method | 山东道可化学有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-108996524-B | Method for preparing bromide salt from bromine-containing waste | 寿光富康制药有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-111892529-A | 6-chloro-5-hydroxyisoindole-1-one and synthesis method thereof | 南通大学 | 2020-11-06 | — | — | CN | claimed |
| CN-108218676-B | Method for synthesizing 4-bromo-3-methylanisole | 清华大学 | 2020-08-18 | — | — | CN | claimed |
| US-20150344486-A1 | PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | CYCLACEL LIMITED (GB) | 2015-12-03 | — | — | US | claimed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | claimed |
| CN-101786956-B | Method for deacylating N-acylated diphenylamine or ring-substituted derivatives thereof | MORIS CHEMICAL CO LTD | 2011-02-16 | — | — | CN | claimed |
| CN-101786956-A | Method for deacylating N-acylated diphenylamine or ring-substituted derivatives thereof | MORIS CHEMICAL CO LTD | 2010-07-28 | — | — | CN | claimed |
| EP-2183239-A1 | SULFONAMIDES AS TRPM8 MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2010-05-12 | — | — | EP | claimed |
| US-20090264474-A1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-10-22 | — | — | US | claimed |
| WO-2009012430-A1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-22 | — | — | WO | claimed |
| EP-1055658-B1 | Process for cis-1- 2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]ethyl pyrrolidine | PFIZER PROD INC (US) | 2003-03-12 | — | — | EP | claimed |
| US-20020042524-A1 | Process for cis-1{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy] ethyl}pyrrolidine | CHIU CHARLES K F (US) | 2002-04-11 | — | — | US | claimed |
| US-6323345-B1 | BROMINATING 2-BROMO-5-METHOXY-TOLUENE TO PROVIDE 1-BROMO-2-BROMOMETHYL-4-METHOXYBENZENE; DECARBOXYLATION, REACTING WITH ETHYLENE GLYCOL; REACTING WITH N-BUTYL LITHIUM AND 4-BENZYLOXY BENZONITRILE; HYDROLYSIS, HYDROGENATION | PFIZER INC. | 2001-11-27 | — | — | US | claimed |
| EP-1055658-A2 | Process for cis-1- 2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]ethyl pyrrolidine | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | claimed |
| US-5008464-A | Anisole bromination | EAST SHORT CHEMICAL COMPANY (US) | 1991-04-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042524-A1 | Process for cis-1{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy] ethyl}pyrrolidine | P4HA1, PAH, DNM1 | MAPT 1877/4885NPC1 815/4885RAB9A 1513/4885 |
| US-20150344486-A1 | PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | DCK, DTYMK, TK1 | MAPT 2501/4885NPC1 2831/4885RAB9A 2853/4885 |
| US-20090264474-A1 | SULFONAMIDES AS TRPM8 MODULATORS | TRPM8, TRPM5, TRPM2 | MAPT 3324/4885NPC1 1670/4885RAB9A 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.