Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10612616 | 0.83 | CYP11B2 (0.50) | ALDH1A1MAPTNAPRTPOLBKMT2A | |
| Isonicotinonitrile SCHEMBL29983434 | 0.82 | GAA (0.49) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| Benzonitrile SCHEMBL28231507 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| Benzonitrile SCHEMBL30798086 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| 3-Methylpyridine SCHEMBL5743407 | 0.82 | NAPRT (0.59) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| SCHEMBL27602928 | 0.80 | BCHE (0.47) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| Pyridine SCHEMBL28273071 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| Pyridine SCHEMBL5968326 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| Pyridine SCHEMBL25354696 | 0.78 | NAPRT (0.69) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| SCHEMBL28728504 | 0.78 | NAPRT (0.54) | ALDH1A1LMNAMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836304-A | Improved oligonucleotide synthesis | 巴克姆股份公司 | 2024-04-05 | — | — | CN | disclosed |