Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 6/20 | 0.77 |
| ▸ | RORC | P51449 | 5/20 | 0.77 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.77 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.77 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.66 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.66 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.66 |
| ▸ | CRYAB | P02511 | 1/20 | 0.63 |
| ▸ | HMGCR | P04035 | 1/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGAV | P06756 | 1/20 | 0.63 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.63 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL291866 | 1.00 | OSBP (0.77) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL28154512 | 0.96 | OSBP (0.83) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL2319114 | 0.96 | OSBP (0.83) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27458126 | 0.96 | OSBP (0.83) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL4735856 | 0.93 | OSBP (0.86) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27486171 | 0.93 | OSBP (0.86) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL246731 | 0.93 | OSBP (0.70) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL10499932 | 0.93 | OSBP (0.70) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL248409 | 0.93 | OSBP (0.70) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27624441 | 0.92 | OSBP (0.91) | OSBPRORCOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036376-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2018-02-08 | — | — | US | claimed |
| US-20150246138-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2015-09-03 | — | — | US | claimed |
| EP-2892509-B1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20220249539-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2022-08-11 | — | — | US | disclosed |
| US-11304964-B2 | Bolaamphiphilic compounds, compositions and uses thereof | LAUREN SCIENCES LLC (US) | 2022-04-19 | — | — | US | disclosed |
| US-20220072098-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2022-03-10 | — | — | US | disclosed |
| EP-2892511-B1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| US-20210106687-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC | 2021-04-15 | — | — | US | disclosed |
| US-20210023009-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN GURION UNIV OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2021-01-28 | — | — | US | disclosed |
| US-10842747-B2 | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery | Ben-Gurion University of Negev R & D (IL) | 2020-11-24 | — | — | US | disclosed |
| EP-3539535-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | Ben-Gurion University of The Negev Research and Development Authority (IL) | 2019-09-18 | — | — | EP | disclosed |
| WO-2014039504-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039501-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| US-20120164072-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2012-06-28 | — | — | US | disclosed |
| EP-2427175-A2 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | Ben-gurion University Of The Negev Research And Development Authority (IL) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128504-A2 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2010-11-11 | — | — | WO | disclosed |
| CN-101848703-A | Improved liposomes and uses thereof | SYNVOLUX IP BV | 2010-09-29 | — | — | CN | disclosed |
| US-6261760-B1 | IDENTIFYING ANTI-MITOTIC AGENTS BY MIXING CELLS WITH A TEST AGENT; DETECTING THE EFFLUX OF FREE CHOLESTEROL BY WHICH CELLS ARE IN CONTACT WITH TEST AGENT AND COMPARE CONCENTRATIONS OF CHOLESTEROL LEVELS WITH CELLS LACKING TEST AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-07-17 | — | — | US | disclosed |
| WO-1999046592-A9 | REGULATION OF THE CELL CYCLE BY STEROLS | UNIV CALIFORNIA (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999046592-A1 | REGULATION OF THE CELL CYCLE BY STEROLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164072-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | TSPO, ANXA6, ANXA11 | OSBP 611/4885RORC 4055/4885OSBP2 1111/4885 |
| US-11304964-B2 | Bolaamphiphilic compounds, compositions and uses thereof | LGALS1, BOLA2; BOLA2B, LGALS2 | OSBP 1420/4885RORC 4306/4885OSBP2 1432/4885 |
| US-20220072098-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | GFRA2, GFRA1, NGF | OSBP 1160/4885RORC 4342/4885OSBP2 1061/4885 |
| US-20210023009-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | TSPO, ANXA6, ANXA11 | OSBP 611/4885RORC 4055/4885OSBP2 1111/4885 |
| US-10842747-B2 | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery | TSPO, ANXA6, ANXA11 | OSBP 611/4885RORC 4055/4885OSBP2 1111/4885 |
| US-20210106687-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LGALS1, BOLA2; BOLA2B, LGALS2 | OSBP 1373/4885RORC 4743/4885OSBP2 1240/4885 |
| US-20150246138-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LGALS1, BOLA2; BOLA2B, LGALS2 | OSBP 394/4885RORC 4310/4885OSBP2 279/4885 |
| US-20220249539-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | BOLA2; BOLA2B, LGALS1, LGALS2 | OSBP 1184/4885RORC 4443/4885OSBP2 1243/4885 |
| US-20180036376-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LGALS1, BOLA2; BOLA2B, LGALS2 | OSBP 394/4885RORC 4310/4885OSBP2 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.