Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187785 | 0.77 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL25791830 | 0.71 | DYRK1A (0.37) | P2RX7OPRL1 | |
| SCHEMBL30320519 | 0.71 | DYRK1A (0.37) | P2RX7OPRL1 | |
| SCHEMBL28645007 | 0.71 | KDM5A (0.35) | P2RX7OPRL1 | |
| SCHEMBL7068629 | 0.66 | MAPT (0.36) | — | |
| SCHEMBL14660835 | 0.66 | NUDT1 (0.49) | — | |
| SCHEMBL18328487 | 0.66 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL23022442 | 0.65 | P2RX7 (0.35) | P2RX7OPRL1 | |
| SCHEMBL11099024 | 0.65 | MRGPRX4 (0.43) | — | |
| SCHEMBL31184367 | 0.65 | OPRL1 (0.32) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052866-B | Crystal form of nitrogen-containing heteroaromatic derivative free alkali | 上海翰森生物医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115353509-B | Nitrogen-containing heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-12 | — | — | CN | disclosed |