SCHEMBL7068629

SCHEMBL7068629

O=C(CS)Oc1ccncc1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
NOD2 Q9HC29 1/20 0.35
KMT2A Q03164 2/20 0.35
ALOX15 P16050 1/20 0.35
ROCK2 O75116 1/20 0.34
ROCK1 Q13464 1/20 0.34
GALR3 O60755 1/20 0.34
NR2F2 P24468 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 2/20 0.33
AGTR1 P30556 2/20 0.33
NOTUM Q6P988 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
CDC25B P30305 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320822 0.79 GAA (0.41) MAPTGAANOD2KMT2AALOX15
SCHEMBL27805730 0.77 KDM4E (0.46) MAPTGAANOD2KMT2AALOX15
SCHEMBL11091140 0.75 PTK2B (0.45) MAPTKMT2AHPGDNPC1RAB9A
SCHEMBL9159636 0.72 TDP1 (0.53) MAPTKMT2AALDH1A1AGTR1HPGD
SCHEMBL9694189 0.72 KMT2A (0.50) MAPTKMT2AALOX15ALDH1A1KDM4E
SCHEMBL11837654 0.71 CYP19A1 (0.53) MAPTGAAKMT2AALDH1A1KDM4E
SCHEMBL11599855 0.70 MRGPRX4 (0.45) MAPTGAAKMT2AALDH1A1KDM4E
SCHEMBL27773816 0.70 GAA (0.37) MAPTGAANOD2KMT2AROCK2
SCHEMBL11601543 0.69 LMNA (0.49) MAPTKMT2AALDH1A1NPC1RAB9A
SCHEMBL7828574 0.69 ALDH1A1 (0.44) MAPTGAAKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518407-B1 Novel reactive dye compound is disclosed. It comprises (a) at least one chromophore moiety; (b) at least one nitrogen-containing heterocycle; (c) a linking group to link each chromophore moiety to each nitrogen-containing heterocycle; THE PROCTER & GAMBLE COMPANY 2003-02-11 US disclosed