SCHEMBL29187948

SCHEMBL29187948

CC(C)(C)c1cc(CCCCCO[Si](C)(C)C(C)(C)C)c(C(=O)O)c(C2CC2)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29187894 0.83 ALDH1A1 (0.33) DUTDGAT1
SCHEMBL29187949 0.78 DUT (0.31) DUT
SCHEMBL23970618 0.71 DUT (0.33) DUTDGAT1
SCHEMBL29187895 0.66 DGAT1 (0.34) DUTDGAT1
SCHEMBL26659619 0.64 FOLH1 (0.46) DUT
SCHEMBL9321614 0.64 GRIN2D (0.50)
SCHEMBL4653272 0.63 HTT (0.42)
SCHEMBL23043928 0.63 GABRP (0.35) DUT
SCHEMBL9320820 0.62 PTGS1 (0.43) DUT
SCHEMBL2352359 0.61 DUT (0.38) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551862-B Macrocyclic inhibitors of peptidyl arginine deiminase 吉利德科学公司 2024-04-12 CN disclosed