Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CETP | P11597 | 7/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190096 | 0.84 | ALDH1A1 (0.34) | PDCD1CD274HPGDTP53CETP | |
| SCHEMBL29190093 | 0.84 | ALDH1A1 (0.34) | PDCD1CD274HPGDTP53CETP | |
| SCHEMBL24820049 | 0.82 | VSIR (0.42) | PDCD1CD274HPGDTP53CETP | |
| SCHEMBL29189889 | 0.79 | ADORA2A (0.34) | HPGDTP53ADORA2AVSIR | |
| SCHEMBL29190018 | 0.77 | ALDH1A1 (0.43) | PDCD1CD274HPGDTP53CETP | |
| SCHEMBL29190020 | 0.76 | CBLB (0.35) | CETPADORA2AP2RX7 | |
| SCHEMBL29190023 | 0.76 | CBLB (0.35) | CETPADORA2AP2RX7 | |
| SCHEMBL29189920 | 0.76 | CD274 (0.35) | PDCD1CD274TP53ADORA2AVSIR | |
| SCHEMBL29190059 | 0.76 | CETP (0.37) | HPGDTP53CETPNPC1RAB9A | |
| SCHEMBL24821901 | 0.75 | VSIR (0.42) | PDCD1CD274HPGDTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |