Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189979 | 1.00 | L3MBTL1 (0.35) | L3MBTL1ATMKDM4ETP53HPGD | |
| SCHEMBL29189986 | 0.90 | S1PR1 (0.36) | CBLBS1PR1S1PR3VSIR | |
| SCHEMBL29189949 | 0.90 | S1PR1 (0.36) | CBLBS1PR1S1PR3VSIR | |
| SCHEMBL29190104 | 0.90 | S1PR1 (0.36) | CBLBS1PR1S1PR3VSIR | |
| SCHEMBL29190117 | 0.89 | MAPT (0.39) | L3MBTL1ATMKDM4ETP53HPGD | |
| SCHEMBL29190058 | 0.89 | MAPT (0.39) | L3MBTL1ATMKDM4ETP53HPGD | |
| SCHEMBL29190061 | 0.89 | MAPT (0.39) | L3MBTL1ATMKDM4ETP53HPGD | |
| SCHEMBL29189931 | 0.88 | VSIR (0.36) | CBLBS1PR1S1PR3VSIR | |
| SCHEMBL29189982 | 0.87 | S1PR1 (0.35) | CBLBS1PR1S1PR3VSIR | |
| SCHEMBL29189916 | 0.87 | S1PR1 (0.35) | CBLBS1PR1S1PR3VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |