Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866741 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL12583947 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL317776 | 0.73 | CYP3A4 (0.42) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL147979 | 0.73 | KIF11 (0.41) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL30152700 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL1768922 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL28362510 | 0.72 | XDH (0.39) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL8903008 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL4914101 | 0.71 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL8902847 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP3A4TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |