Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936789 | 0.86 | SRD5A2 (0.58) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL2419793 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29190948 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29190958 | 0.83 | HTT (0.73) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29191041 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL30874537 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29190971 | 0.82 | ALDH1A1 (0.72) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29190945 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL8460916 | 0.81 | RAB9A (0.63) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL29190947 | 0.79 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |