Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29192912 | 0.85 | HTT (0.44) | AKR1C3AKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL28892095 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1CRHBPCRHR2CA1 | |
| SCHEMBL29192951 | 0.78 | LMNA (0.54) | AKR1C3AKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL30825404 | 0.78 | LMNA (0.54) | AKR1C3AKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL29192902 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL8654849 | 0.78 | TDP1 (0.65) | ALDH1A1TDP1CRHBPCRHR2L3MBTL1 | |
| SCHEMBL1984350 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1CRHBPCRHR2L3MBTL1 | |
| SCHEMBL9423180 | 0.76 | AKR1C3 (0.70) | AKR1C3AKR1C2AKR1C1ALDH1A1GPR35 | |
| SCHEMBL6781590 | 0.76 | PTGDR2 (0.52) | ALDH1A1TDP1CA1CA2MEN1 | |
| SCHEMBL100456 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1CRHBPCRHR2S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |