Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29192951 | 1.00 | LMNA (0.54) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL29193120 | 0.79 | ALDH1A1 (0.43) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL29193157 | 0.78 | AKR1C3 (0.49) | MAPTALDH1A1TDP1AKR1C3AKR1C2 | |
| SCHEMBL19585480 | 0.78 | MAPT (0.57) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL2963618 | 0.78 | ALDH1A1 (0.56) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL28892095 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1TDP1CYP3A4HIF1A | |
| SCHEMBL8654849 | 0.74 | TDP1 (0.65) | ALDH1A1TDP1CYP3A4TSHRPOLB | |
| SCHEMBL10058719 | 0.74 | RXRA (0.51) | ALDH1A1HPGDAKR1C3AKR1C2PTGDR2 | |
| SCHEMBL27739400 | 0.73 | KIF11 (0.53) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL6781590 | 0.72 | PTGDR2 (0.52) | LMNAMAPTALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |