Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29193157 | 0.85 | AKR1C3 (0.49) | ALDH1A1KMT2AMEN1TDP1KDM4E | |
| SCHEMBL27826601 | 0.80 | HTT (0.45) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL17987532 | 0.78 | ALDH1A1 (0.54) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL30000843 | 0.77 | PDGFRB (0.45) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL29192902 | 0.77 | ALDH1A1 (0.45) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL31057272 | 0.76 | PKM (0.42) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL2484847 | 0.74 | VCAM1 (0.57) | ALDH1A1KMT2AHPGDMEN1TDP1 | |
| SCHEMBL31027932 | 0.73 | ERN1 (0.44) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8070346 | 0.72 | PDGFRB (0.55) | HTTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL23925436 | 0.72 | MEN1 (0.52) | ALDH1A1KMT2AMEN1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |