Methane

Methane

SCHEMBL29193641

C.CNc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.55
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 2/20 0.55
KIF11 P52732 2/20 0.50
HSD17B10 Q99714 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
TSHR P16473 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
HTR6 P50406 1/20 0.41
MAPT P10636 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
APP P05067 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2543902 0.97 CYP3A4 (0.58) CYP3A4ALDH1A1TDP1TP53KIF11
Benzidine SCHEMBL7896409 0.97 CYP3A4 (0.58) CYP3A4ALDH1A1TDP1TP53KIF11
SCHEMBL20048273 0.97 CYP3A4 (0.58) CYP3A4ALDH1A1TDP1TP53KIF11
SCHEMBL525926 0.89
Hydrochloric Acid SCHEMBL1154858 0.87 TSHR (0.48) CYP3A4ALDH1A1TDP1TP53KIF11
Ammonia Solution, Strong SCHEMBL11052046 0.87 TSHR (0.48) CYP3A4ALDH1A1TDP1TP53KIF11
Hydrochloric Acid SCHEMBL6010014 0.87 TSHR (0.48) CYP3A4ALDH1A1TDP1TP53KIF11
SCHEMBL5147226 0.84 KIF11 (0.64) CYP3A4ALDH1A1TP53KIF11HSD17B10
SCHEMBL7011380 0.83 CYP3A4 (0.45) CYP3A4ALDH1A1TDP1TP53KIF11
SCHEMBL8942483 0.82 MAPT (0.61) CYP3A4ALDH1A1TDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117654548-A Method for regenerating catalyst for producing diamino dicyclohexyl methane 万华化学集团股份有限公司 2024-03-08 CN disclosed