Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195509 | 0.83 | GRIN2D (0.53) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL20689407 | 0.79 | CRHBP (0.66) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL21238774 | 0.77 | CRHBP (0.69) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL24815805 | 0.76 | KMT2A (0.41) | MAPTKMT2AGBA1KDM4EALDH1A1 | |
| SCHEMBL18277835 | 0.76 | GRIN2D (0.57) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL22148686 | 0.75 | GRIN2D (0.50) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL24817000 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2MAPTALDH1A1NPSR1 | |
| SCHEMBL6440936 | 0.71 | GRIN2D (1.00) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL20697275 | 0.70 | HRH4 (0.48) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL24816957 | 0.69 | GRIN2D (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |