Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457057 | 1.00 | TRPA1 (0.43) | TRPA1SMN1; SMN2TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL3669411 | 0.81 | ALDH1A1 (0.39) | TRPA1SLC6A4TSHR | |
| SCHEMBL25955883 | 0.81 | THRB (0.33) | TRPA1SLC6A4CYP2C19 | |
| SCHEMBL3077663 | 0.81 | TRPA1 (0.54) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL8087389 | 0.81 | TRPA1 (0.54) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL6876618 | 0.81 | TRPA1 (0.46) | TRPA1SMN1; SMN2TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL250981 | 0.81 | TRPA1 (0.46) | TRPA1SMN1; SMN2TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL6876621 | 0.81 | EPHX1 (0.43) | SMN1; SMN2TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL5672807 | 0.81 | TRPA1 (0.46) | TRPA1SMN1; SMN2TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL253328 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2TAAR1SIGMAR1SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683082-A | Engineered cytolytic immune cells | 奥托路斯有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-111954813-B | Engineered cytolytic immune cells | 奥托路斯有限公司 | 2024-01-19 | — | — | CN | disclosed |