Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876618 | 1.00 | TRPA1 (0.46) | TRPA1SMN1; SMN2CYP2C19CYP1A2EPHX1 | |
| SCHEMBL5672807 | 1.00 | TRPA1 (0.46) | TRPA1SMN1; SMN2CYP2C19CYP1A2EPHX1 | |
| SCHEMBL20901018 | 0.81 | TDP1 (0.42) | SMN1; SMN2CYP2C19TSHRATML3MBTL1 | |
| SCHEMBL13721525 | 0.81 | TRPA1 (0.58) | TRPA1CYP1A2EPHX1TSHRALPI | |
| SCHEMBL5161982 | 0.81 | TRPA1 (0.58) | TRPA1CYP1A2EPHX1TSHRALPI | |
| SCHEMBL29197870 | 0.81 | TRPA1 (0.43) | TRPA1SMN1; SMN2CYP2C19EPHX1TSHR | |
| SCHEMBL253328 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19CYP1A2EPHX1TSHR | |
| SCHEMBL17457057 | 0.81 | TRPA1 (0.43) | TRPA1SMN1; SMN2CYP2C19EPHX1TSHR | |
| SCHEMBL6876621 | 0.81 | EPHX1 (0.43) | SMN1; SMN2CYP2C19EPHX1TSHRATM | |
| SCHEMBL28891867 | 0.81 | TRPA1 (0.46) | TRPA1CYP1A2EPHX1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210069071-A1 | COSMETIC SOAP GEL STICKS WITH IMPROVED MANUFACTURABILITY | HENKEL AG & CO. KGAA (DE) | 2021-03-11 | — | — | US | claimed |
| EP-2453867-A2 | COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT | Henkel AG & Co. KGaA (DE) | 2012-05-23 | — | — | EP | claimed |
| EP-2349185-A2 | MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY | Henkel AG & Co. KGaA (DE) | 2011-08-03 | — | — | EP | claimed |
| EP-2349184-A2 | MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL | Henkel AG & Co. KGaA (DE) | 2011-08-03 | — | — | EP | claimed |
| WO-2011006689-A2 | COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT | HENKEL AG & CO. KGAA (DE) | 2011-01-20 | — | — | WO | claimed |
| WO-2010009976-A2 | MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL | HENKEL AG & CO. KGAA (DE) | 2010-01-28 | — | — | WO | claimed |
| WO-2010009977-A2 | MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY | HENKEL AG & CO. KGAA (DE) | 2010-01-28 | — | — | WO | claimed |
| US-11504309-B2 | Deo emulsion for aerosols, deodorant comprising the same and use of the deodorant | HENKEL AG & CO. KGAA (DE) | 2022-11-22 | — | — | US | disclosed |
| US-11324675-B2 | Deo emulsion for aerosols with reduced stain problem, deodorant comprising the same and use of the deodorant | HENKEL AG & CO. KGAA (DE) | 2022-05-10 | — | — | US | disclosed |
| US-11090237-B2 | Deodorant cosmetic compositions comprising calcium silicate and sodium bicarbonate | HENKEL AG & CO. KGAA (DE) | 2021-08-17 | — | — | US | disclosed |
| US-11045399-B2 | Residue-minimized antiperspirant composition with improved skin feel | HENKEL AG & CO. KGAA (DE) | 2021-06-29 | — | — | US | disclosed |
| US-20210093521-A1 | ANTIBACTERIAL ACTIVITY BY MG COMPLEX IN DEODORANT EMULSION FOR AEROSOLS, DEODORANT INCLUDING THE SAME AND USE OF THE DEODORANT | HENKEL AG & CO. KGAA (DE) | 2021-04-01 | — | — | US | disclosed |
| US-20210093522-A1 | DEO EMULSION FOR AEROSOLS WITH REDUCED STAIN PROBLEM, DEODORANT COMPRISING THE SAME AND USE OF THE DEODORANT | HENKEL AG & CO. KGAA (DE) | 2021-04-01 | — | — | US | disclosed |
| US-6881868-B2 | Reacting an benzaldehyde and an alkyl ester to form a chemical intermediate stereoselective, for the preparation of antihypertensive agents; hydroxylation, acylation, alkenylation, hydrogenation | SPEEDEL PHARMA AG (CH) | 2005-04-19 | — | — | US | disclosed |
| US-20040092766-A1 | Stereoselective addition of propionic acid esters to benzaldehydes to form hydroxypropionic esters; dehydroxylation; reduction to corresponding allyl alcohols; enantioselective hydrogenation | SPEEDEL PHARMA AG (CH) | 2004-05-13 | — | — | US | disclosed |
| US-20040092766-A1 | Stereoselective addition of propionic acid esters to benzaldehydes to form hydroxypropionic esters; dehydroxylation; reduction to corresponding allyl alcohols; enantioselective hydrogenation | SPEEDEL PHARMA AG (CH) | 2004-05-13 | — | — | US | disclosed |
| CN-1440374-A | Process for perparation of (R)-2-alkyl-3-phenyl-1-propanols | SPEEDEL PHARMA AG (CH) | 2003-09-03 | — | — | CN | disclosed |
| EP-1296912-A1 | PROCESS FOR THE PREPARATION OF (R)-2-ALKYL-3-PHENYL-1-PROPANOLS | Speedel Pharma AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002487-A1 | PROCESS FOR THE PREPARATION OF (R)-2-ALKYL-3-PHENYL-1-PROPANOLS | SPEEDEL PHARMA AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| US-4434076-A | QUATERNARY AMMONIUM-SMECTITE COMPLEXES | NL INDUSTRIES, INC. (US) | 1984-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092766-A1 | Stereoselective addition of propionic acid esters to benzaldehydes to form hydroxypropionic esters; dehydroxylation; reduction to corresponding allyl alcohols; enantioselective hydrogenation | ADH1C, ADH5, ADH1A | TRPA1 3076/4885SMN1; SMN2 4819/4885CYP2C19 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.