Racemethionine

Racemethionine

SCHEMBL291985

CSCCC(N)C(=O)O.O=S(=O)(O)O

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.50
PMP22 Q01453 2/20 0.50
BHMT2 Q9H2M3 1/20 0.50
RNPEP Q9H4A4 1/20 0.48
NOS2 P35228 3/20 0.46
NOS3 P29474 2/20 0.46
NOS1 P29475 2/20 0.46
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
CYP1A2 P05177 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL23930380 1.00 BHMT (0.50) BHMTPMP22BHMT2RNPEPNOS2
Methionine SCHEMBL291986 1.00 BHMT (0.50) BHMTPMP22BHMT2RNPEPNOS2
Methionine SCHEMBL9192308 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Racemethionine SCHEMBL9190291 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Methionine SCHEMBL28118990 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Racemethionine SCHEMBL9192305 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Racemethionine SCHEMBL8463168 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Racemethionine SCHEMBL29172847 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Methionine SCHEMBL1764849 0.98 BHMT (0.49) BHMTPMP22BHMT2RNPEPNOS2
Methionine SCHEMBL7781670 0.96 RNPEP (0.50) BHMTPMP22BHMT2RNPEPNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106798157-A A kind of fleshy duck fodder of rice-type and preparation method thereof 广东温氏食品集团股份有限公司 2017-06-06 CN claimed
US-9534010-B2 Stable indole-3-propionate salts of S-adenosyl-L-methionine HEBERT SAM-E LLC 2017-01-03 US claimed
CN-1135297-A Application of methionine sulfate metal matches in bullog cultivation HUNAN CHEMICAL ACADEMY (CN) 1996-11-13 CN claimed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 EP disclosed
US-12137716-B2 Methods of liver disease treatment HUDNALL MICHAEL (US) 2024-11-12 US disclosed
EP-4417620-A1 METHOD FOR PRODUCING ANTIBODY POPULATION Prestige Biologics Co., Ltd. (KR) 2024-08-21 EP disclosed
US-20240254534-A1 METHOD FOR PRODUCING ANTIBODY POPULATION PRESTIGE BIOLOGICS CO., LTD. (KR) 2024-08-01 US disclosed
CN-118369337-A Method for producing antibody population 普莱斯蒂生物制品有限公司 2024-07-19 CN disclosed
EP-4304643-A1 COMPOSITIONS AND METHODS FOR REDUCING IMMUNE INTOLERANCE Lapix Therapeutics, Inc. (US) 2024-01-17 EP disclosed
WO-2024005767-A1 A TASTE MASKED SOLID COMPOSITION OF ZINC ACTIVE ABDI IBRAHIM ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2024-01-04 WO disclosed
EP-3708178-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2023-10-04 EP disclosed
WO-2002010206-A2 NUCLEOTIDE SEQUENCES WHICH CODE FOR THE METF GENE DEGUSSA AG (DE) 2002-02-07 WO disclosed
US-5670549-A Prevention and amelioration of liver toxicity with beta-carotene EPITEK, INC. 1997-09-23 US disclosed
CN-1156410-A Anti-stress, anti-injury and anti-aging medicine and production method thereof RIGA D (RO) 1997-08-06 CN disclosed
CN-1135297-A Application of methionine sulfate metal matches in bullog cultivation HUNAN CHEMICAL ACADEMY (CN) 1996-11-13 CN disclosed
CN-1135297-A Application of methionine sulfate metal matches in bullog cultivation HUNAN CHEMICAL ACADEMY (CN) 1996-11-13 CN disclosed
WO-1994010992-A1 PREVENTION AND AMELIORATION OF ACETAMINOPHEN TOXICITY WITH BETA-CAROTENE BARANOWITZ STEVEN A (US) 1994-05-26 WO disclosed
US-5260340-A Prevention and amelioration of acetaminophen toxicity with beta-carotene EPITEK, INC. 1993-11-09 US disclosed
EP-0419238-A1 Antibodies and proteins THE WELLCOME FOUNDATION LIMITED (GB) 1991-03-27 EP disclosed
US-4067994-A FEED SUPPLEMENTS ZINPRO CORPORATION (US) 1978-01-10 US disclosed