Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245696 | 0.76 | TSHR (0.52) | ALOX15TSHRPOLBCYP1A2CYP2D6 | |
| SCHEMBL29198545 | 0.76 | CA2 (0.38) | ALOX15TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL8022137 | 0.71 | POLB (0.57) | POLBCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL12278977 | 0.69 | HSPA5 (0.43) | ALOX15TSHRPOLBCYP1A2CYP2D6 | |
| SCHEMBL9124039 | 0.68 | POLB (0.44) | POLBCYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL1372190 | 0.68 | GABRA1 (0.35) | ALOX15TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31683792 | 0.67 | ALOX15 (0.54) | ALOX15TSHRPOLBCYP1A2CYP2C19 | |
| SCHEMBL77392 | 0.66 | POLB (0.61) | POLBMEN1KMT2AMAOAMAOB | |
| SCHEMBL30937520 | 0.66 | TAAR1 (0.37) | ALOX15TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL1398159 | 0.66 | TAAR1 (0.37) | ALOX15TSHRSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014851-B | Fluorene azole structural compound and application thereof | 北京燕化集联光电技术有限公司 | 2024-02-27 | — | — | CN | disclosed |