Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474513 | 0.97 | PSIP1 (0.42) | PSIP1GAAKIF11CSF1RALDH1A1 | |
| SCHEMBL28349856 | 0.84 | PSIP1 (0.44) | PSIP1GAAKIF11CA1CA2 | |
| SCHEMBL28137915 | 0.78 | PLA2G2A (0.46) | MAPK8 | |
| SCHEMBL18038517 | 0.75 | MAP2K2 (0.41) | MAPK8 | |
| SCHEMBL28352399 | 0.72 | PSIP1 (0.53) | PSIP1GAAKIF11CSF1RALDH1A1 | |
| SCHEMBL25365514 | 0.72 | SLC6A2 (0.43) | CA1CA2CA9AURKA | |
| SCHEMBL30842565 | 0.72 | KMT2A (0.44) | ALDH1A1CA1CA2CA9POLB | |
| SCHEMBL28349448 | 0.69 | PSIP1 (0.42) | PSIP1GAAKIF11ALDH1A1RORC | |
| Diethylamine SCHEMBL7220117 | 0.69 | MAP2K2 (0.40) | ALDH1A1KDRFLT4MAPK8 | |
| SCHEMBL5072652 | 0.69 | CA2 (0.53) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |