Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | F2R | P25116 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616638 | 0.99 | HTR2C (0.38) | HTR2CKIF11NOTUMKDM1ARCOR1 | |
| SCHEMBL21616589 | 0.99 | HTR2C (0.38) | HTR2CKIF11NOTUMKDM1ARCOR1 | |
| SCHEMBL30474495 | 0.98 | HTR2C (0.38) | HTR2CKIF11NOTUMKDM1ARCOR1 | |
| SCHEMBL21616599 | 0.83 | KIF11 (0.41) | HTR2CKIF11KDM1AMAOBF2R | |
| SCHEMBL30474483 | 0.83 | FPR1 (0.39) | HTR2CKIF11KDM1ARCOR1MAOB | |
| SCHEMBL30474420 | 0.83 | FPR1 (0.39) | HTR2CKIF11KDM1ARCOR1MAOB | |
| SCHEMBL28525708 | 0.81 | ENPP2 (0.44) | HTR2C | |
| SCHEMBL28531773 | 0.81 | ENPP2 (0.44) | HTR2C | |
| SCHEMBL23631897 | 0.80 | KDM4E (0.46) | F2RKDM4EALDH1A1POLBGAA | |
| SCHEMBL28537466 | 0.80 | KDM4E (0.46) | F2RKDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |