Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200545 | 0.92 | KDM4E (0.37) | MAPTGAAKDM4ETP53HTT | |
| SCHEMBL29200502 | 0.87 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DPARP15 | |
| SCHEMBL29200576 | 0.86 | ALDH1A1 (0.40) | MAPTGAAKDM4EHTTALDH1A1 | |
| SCHEMBL29200547 | 0.83 | KDM4E (0.54) | MAPTGAAKDM4EHTTALDH1A1 | |
| SCHEMBL28548642 | 0.83 | MAPT (0.45) | MAPTGAAPDE4APDE4BPDE4C | |
| SCHEMBL29200485 | 0.80 | IRAK4 (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28509702 | 0.76 | ALDH1A1 (0.43) | MAPTGAAKDM4EHTTALDH1A1 | |
| SCHEMBL28517495 | 0.75 | MAPT (0.46) | MAPTGAAKDM4EALDH1A1PRSS1 | |
| SCHEMBL28548656 | 0.75 | MAPT (0.42) | MAPTGAAKDM4ETP53HTT | |
| SCHEMBL30803074 | 0.72 | PARP15 (0.46) | MAPTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |