Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200495 | 0.92 | MAPT (0.38) | KDM4EMAPTGAATP53HTT | |
| SCHEMBL29200485 | 0.88 | IRAK4 (0.33) | IRAK4STING1 | |
| SCHEMBL29200576 | 0.84 | ALDH1A1 (0.40) | KDM4EMAPTGAAHTTALDH1A1 | |
| SCHEMBL29200547 | 0.84 | KDM4E (0.54) | KDM4EMAPTGAAHTTALDH1A1 | |
| SCHEMBL28548656 | 0.84 | MAPT (0.42) | KDM4EMAPTGAATP53HTT | |
| SCHEMBL29200502 | 0.80 | PDE4A (0.38) | — | |
| SCHEMBL28548646 | 0.77 | MAPT (0.41) | KDM4EMAPTGAATP53HTT | |
| SCHEMBL28548642 | 0.75 | MAPT (0.45) | MAPTGAATP53HTTALDH1A1 | |
| SCHEMBL28509702 | 0.74 | ALDH1A1 (0.43) | KDM4EMAPTGAAHTTALDH1A1 | |
| SCHEMBL21158078 | 0.74 | LMNA (0.41) | KDM4EMAPTGAATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |