Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19773692 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL17000204 | 0.81 | — | — | |
| SCHEMBL3258617 | 0.80 | SLC6A4 (0.49) | ROCK1 | |
| SCHEMBL4327140 | 0.74 | UHRF1 (0.48) | ROCK1ADRB2CIT | |
| SCHEMBL20508491 | 0.74 | UHRF1 (0.48) | ROCK1ADRB2CIT | |
| SCHEMBL4322612 | 0.74 | NOS3 (0.50) | ROCK1ADRB2CITCBLB | |
| SCHEMBL25299834 | 0.72 | ADRB2 (0.35) | ROCK1ADRB2CIT | |
| SCHEMBL20771993 | 0.72 | LOXL2 (0.44) | ROCK1ADRB2CIT | |
| SCHEMBL4340117 | 0.72 | LOXL2 (0.44) | ROCK1ADRB2CIT | |
| SCHEMBL20508509 | 0.72 | LOXL2 (0.44) | ROCK1ADRB2CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659022-A | Ureido substituted pyridine compound, pharmaceutical composition containing ureido substituted pyridine compound and medical application of ureido substituted pyridine compound | 苏州阿尔脉生物科技有限公司 | 2024-03-08 | — | — | CN | disclosed |