Pyrimidine

Pyrimidine

SCHEMBL29201194

C=CN1CCNCC1.c1cncnc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLD1 Q13393 2/20 0.35
ADRB2 P07550 2/20 0.34
NCF1 P14598 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CHRNB2 P17787 3/20 0.34
CHRNA4 P43681 3/20 0.34
HTR3A P46098 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
KCNA5 P22460 1/20 0.31
KCNH2 Q12809 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR2C P28335 1/20 0.31
HTR7 P34969 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28202857 0.88 PLD1 (0.39) PLD1ADRB2NCF1KDM4EALDH1A1
SCHEMBL24380 0.80
Ammonia Solution, Strong SCHEMBL28779669 0.78
Piperazine SCHEMBL28114722 0.78 HIF1A (0.35) HTR3AHTR3EHTR3BADRB1HTR3D
Hydrochloric Acid SCHEMBL7468053 0.78 ALDH1A1 (0.32) KDM4EALDH1A1HTR3AHTR3EHTR3B
Pyrimidine SCHEMBL29085947 0.76 PLD1 (0.40) PLD1ADRB2NCF1KDM4EALDH1A1
SCHEMBL17313543 0.76 PLD1 (0.43) PLD1ADRB2NCF1KDM4EALDH1A1
SCHEMBL17085839 0.75 HIF1A (0.33) HTR3AHTR3EHTR3BADRB1HTR3D
Oxazole SCHEMBL29287401 0.74 ADRB2 (0.31) PLD1ADRB2NCF1
SCHEMBL29110713 0.73 ADRB1 (0.33) HTR3AHTR3EHTR3BADRB1HTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117625051-A Double-sided adhesive sheet 日东电工株式会社 2024-03-01 CN disclosed