Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769201 | 0.80 | NPSR1 (0.50) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL18040073 | 0.78 | TSHR (0.52) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL5366626 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL6607473 | 0.78 | NPSR1 (0.52) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL1465773 | 0.77 | MEN1 (0.54) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL5644547 | 0.76 | OPRM1 (0.42) | GSK3BCA1CA2SIGMAR1ALDH1A1 | |
| SCHEMBL1769917 | 0.76 | HSD11B1 (0.51) | GSK3BKMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19207553 | 0.75 | AKR1C1 (0.52) | GSK3BMEN1KMT2ALMNANPSR1 | |
| SCHEMBL30768288 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL1769341 | 0.74 | LMNA (0.64) | MEN1KMT2ATSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703758-B | Compounds used as kinase inhibitors, preparation method and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |