Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171254 | 0.98 | EPHX2 (0.43) | EPHX2HSD11B1SLC22A12DHODHHDAC6 | |
| SCHEMBL29427008 | 0.98 | EPHX2 (0.43) | EPHX2HSD11B1SLC22A12DHODHHDAC6 | |
| SCHEMBL18963844 | 0.83 | SLC22A12 (0.37) | EPHX2HSD11B1SLC22A12DHODHHDAC6 | |
| SCHEMBL8977118 | 0.80 | L3MBTL1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL799554 | 0.77 | CA2 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL15624412 | 0.75 | TRPV1 (0.47) | EPHX2TRPV1 | |
| SCHEMBL2083721 | 0.74 | P2RX7 (0.39) | HSD11B1ALDH1A1TDP1 | |
| SCHEMBL31009386 | 0.73 | EPHX2 (0.44) | EPHX2HSD11B1NFE2L2ALDH1A1TDP1 | |
| SCHEMBL610024 | 0.73 | EPHX2 (0.44) | EPHX2HSD11B1NFE2L2ALDH1A1TDP1 | |
| SCHEMBL8436654 | 0.73 | EPHX2 (0.44) | EPHX2HSD11B1NFE2L2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |