Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29201434 | 0.96 | ALDH1A1 (0.35) | ALDH1A1ALOX15MAPK1TAAR1ESR1 | |
| Iodide SCHEMBL29201303 | 0.96 | ALDH1A1 (0.35) | ALDH1A1ALOX15MAPK1TAAR1ESR1 | |
| SCHEMBL11606388 | 0.79 | KIF11 (0.31) | ALDH1A1TAAR1KCNN4 | |
| Hydrochloric Acid SCHEMBL29201384 | 0.74 | SLC6A2 (0.40) | ALDH1A1TAAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29201342 | 0.71 | FDPS (0.31) | — | |
| Bromide SCHEMBL29201371 | 0.70 | SLC6A2 (0.40) | ALDH1A1TAAR1CYP3A4 | |
| Iodide SCHEMBL29201398 | 0.70 | SLC6A2 (0.40) | ALDH1A1TAAR1CYP3A4 | |
| SCHEMBL8754884 | 0.67 | ALDH1A1 (0.39) | ALDH1A1ALOX15MAPK1TAAR1KMT2A | |
| Iodide SCHEMBL3933539 | 0.66 | FDPS (0.31) | — | |
| Bromide SCHEMBL29201372 | 0.66 | FDPS (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |