Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816856 | 1.00 | KDM4E (0.55) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL16826896 | 0.84 | KDM4E (0.54) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL30816895 | 0.80 | SIGMAR1 (0.60) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL30816869 | 0.80 | SIGMAR1 (0.60) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL30864070 | 0.80 | SIGMAR1 (0.60) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL606956 | 0.79 | LMNA (0.66) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL12781846 | 0.78 | KDM4E (0.66) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL29201748 | 0.78 | KDM4E (0.66) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL29201752 | 0.77 | KDM4E (0.56) | KDM4ESIGMAR1MC4RLMNAPOLB | |
| SCHEMBL29201751 | 0.77 | KDM4E (0.56) | KDM4ESIGMAR1MC4RLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |