Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075951 | 0.93 | ALDH1A1 (0.44) | TPSAB1TPSD1TPSG1CHRM2CHRM1 | |
| SCHEMBL27035708 | 0.89 | GPR119 (0.49) | GPR119FAAHHPGD | |
| SCHEMBL1532854 | 0.87 | ITGB3 (0.55) | TPSAB1TPSD1TPSG1GNAO1GPR119 | |
| SCHEMBL27121409 | 0.87 | DDB1 (0.41) | TPSAB1TPSD1TPSG1CHRM2CHRM1 | |
| SCHEMBL27120931 | 0.87 | GPR119 (0.49) | GPR119FAAHHPGD | |
| SCHEMBL2386299 | 0.86 | CACNA2D1 (0.47) | TPSAB1TPSD1TPSG1CHRM2CHRM1 | |
| SCHEMBL27124732 | 0.85 | EPHX2 (0.43) | TPSAB1TPSD1TPSG1CHRM2CHRM1 | |
| SCHEMBL15000860 | 0.84 | GNAI3 (0.51) | GNAO1GPR119FAAHNR1H2ITGB3 | |
| SCHEMBL27307597 | 0.84 | CACNA2D1 (0.45) | TPSAB1TPSD1TPSG1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL1532657 | 0.83 | GNAI3 (0.53) | GNAO1GPR119FAAHNR1H2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |