Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201704 | 0.90 | LTA4H (0.52) | BCHEEGFRHTR4 | |
| SCHEMBL5149816 | 0.87 | ALDH1A1 (0.47) | BCHEACHE | |
| SCHEMBL29201705 | 0.84 | EGFR (0.45) | BCHEEGFRHTR4 | |
| SCHEMBL11128528 | 0.81 | EGFR (0.58) | EGFR | |
| SCHEMBL29201713 | 0.81 | EGFR (0.47) | BCHEEGFR | |
| SCHEMBL12869921 | 0.80 | EGFR (0.60) | EGFR | |
| SCHEMBL458148 | 0.79 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL24233699 | 0.79 | KDM4E (0.51) | ACHEEGFR | |
| SCHEMBL658800 | 0.78 | LTA4H (0.59) | EGFRKCNH2 | |
| SCHEMBL7060557 | 0.78 | HTT (0.49) | BCHEACHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |