Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201704 | 0.86 | LTA4H (0.52) | EGFRHTR4NOTUMBCHE | |
| SCHEMBL29201713 | 0.85 | EGFR (0.47) | EGFRNOTUMCHRM1SLC6A2HRH2 | |
| SCHEMBL29201765 | 0.84 | BCHE (0.47) | EGFRHTR4BCHE | |
| SCHEMBL11128528 | 0.80 | EGFR (0.58) | EGFRKMT2ANOTUMCHRM1SLC6A2 | |
| SCHEMBL1069985 | 0.80 | SMN1; SMN2 (0.67) | MEN1KMT2A | |
| SCHEMBL12869921 | 0.79 | EGFR (0.60) | EGFRKMT2ANOTUMSIGMAR1HRH3 | |
| SCHEMBL24233699 | 0.78 | KDM4E (0.51) | EGFRNOTUMCHRM1SLC6A2HRH2 | |
| SCHEMBL658800 | 0.77 | LTA4H (0.59) | EGFRMEN1KMT2ASIGMAR1 | |
| SCHEMBL6605317 | 0.77 | SIGMAR1 (0.51) | EGFRNOTUMCHRM1SLC6A2HRH2 | |
| SCHEMBL11114975 | 0.77 | ALDH1A1 (0.49) | EGFRMEN1KMT2ANOTUMCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |