Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201765 | 0.90 | BCHE (0.47) | EGFRHTR4BCHE | |
| SCHEMBL25221091 | 0.86 | SMN1; SMN2 (0.49) | LTA4HALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL29201705 | 0.86 | EGFR (0.45) | EGFRHTR4NOTUMBCHE | |
| SCHEMBL11128528 | 0.83 | EGFR (0.58) | LTA4HEGFRNOTUMALDH1A1MAPK1 | |
| SCHEMBL29201713 | 0.83 | EGFR (0.47) | EGFRNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6605317 | 0.82 | SIGMAR1 (0.51) | LTA4HEGFRNOTUMALDH1A1MAPK1 | |
| SCHEMBL12869921 | 0.82 | EGFR (0.60) | EGFRNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24233699 | 0.81 | KDM4E (0.51) | EGFRNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL658800 | 0.80 | LTA4H (0.59) | LTA4HEGFRALDH1A1 | |
| SCHEMBL11114975 | 0.80 | ALDH1A1 (0.49) | EGFRNOTUMALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |