Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201838 | 0.78 | BPTF (0.68) | BPTFHSD11B1TSHREPHX1EPHX2 | |
| SCHEMBL29265199 | 0.78 | EPHX2 (0.42) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL23277543 | 0.74 | EPHX2 (0.38) | EPHX1EPHX2ALDH1A1MAPT | |
| SCHEMBL29265195 | 0.71 | MAPT (0.48) | TSHRALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28429128 | 0.70 | TEAD1 (0.45) | ALDH1A1 | |
| SCHEMBL7442420 | 0.69 | GPR119 (0.49) | EPHX1HPGDSMN1; SMN2 | |
| SCHEMBL8749014 | 0.68 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1LMNA | |
| SCHEMBL31119839 | 0.68 | BPTF (0.72) | BPTFHSD11B1TSHREPHX1EPHX2 | |
| SCHEMBL12204818 | 0.68 | BPTF (0.72) | BPTFHSD11B1TSHRALDH1A1LMNA | |
| SCHEMBL8799134 | 0.68 | BPTF (0.66) | BPTFHSD11B1TSHREPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447466-A | Oxazole compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-01-26 | — | — | CN | disclosed |