Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205146 | 0.89 | KDM1A (0.34) | PROKR1 | |
| SCHEMBL29205135 | 0.87 | LSS (0.40) | ALDH1A1TP53SMN1; SMN2KMT2A | |
| SCHEMBL29205204 | 0.84 | GRM5 (0.36) | PROKR1 | |
| SCHEMBL29205168 | 0.84 | MCHR1 (0.40) | ALDH1A1TP53ADRB2 | |
| SCHEMBL29205180 | 0.84 | PROKR1 (0.34) | PROKR1GPR119MEN1KMT2A | |
| SCHEMBL29205126 | 0.83 | ALOX5 (0.36) | PROKR1 | |
| SCHEMBL30055420 | 0.81 | MGLL (0.40) | MEN1KMT2A | |
| SCHEMBL29205190 | 0.81 | MGLL (0.40) | MEN1KMT2A | |
| SCHEMBL29205161 | 0.81 | PROKR1 (0.42) | PROKR1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL29205170 | 0.80 | PROKR1 (0.35) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |