Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205126 | 0.88 | ALOX5 (0.36) | PROKR1 | |
| SCHEMBL27166033 | 0.87 | PROKR1 (0.44) | PROKR1MGLL | |
| SCHEMBL29205146 | 0.87 | KDM1A (0.34) | PROKR1KDM1A | |
| SCHEMBL29205170 | 0.86 | PROKR1 (0.35) | PROKR1 | |
| SCHEMBL27166076 | 0.84 | HSD11B1 (0.43) | GRM5MGLL | |
| SCHEMBL29205180 | 0.84 | PROKR1 (0.34) | PROKR1 | |
| SCHEMBL29205160 | 0.84 | PROKR1 (0.34) | PROKR1 | |
| SCHEMBL29205171 | 0.81 | F2R (0.45) | KDM1AMGLL | |
| SCHEMBL29205143 | 0.81 | HSD11B1 (0.40) | MGLL | |
| SCHEMBL30055083 | 0.79 | HSD11B1 (0.44) | GRM5GRM3HSP90AA1HSP90AB1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |