Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205160 | 0.89 | PROKR1 (0.34) | PROKR1 | |
| SCHEMBL27166109 | 0.88 | PROKR1 (0.44) | PROKR1 | |
| SCHEMBL29205204 | 0.87 | GRM5 (0.36) | KDM1APROKR1 | |
| SCHEMBL29205180 | 0.87 | PROKR1 (0.34) | PROKR1RAB9AEGLN1POLB | |
| SCHEMBL29205126 | 0.84 | ALOX5 (0.36) | PROKR1HRH3PRMT5 | |
| SCHEMBL29205142 | 0.83 | MCHR1 (0.40) | PROKR1HPGD | |
| SCHEMBL29205170 | 0.82 | PROKR1 (0.35) | PROKR1 | |
| SCHEMBL27204453 | 0.81 | HSD11B1 (0.39) | RETLMNA | |
| SCHEMBL27166114 | 0.81 | HSD11B1 (0.39) | RETLMNA | |
| SCHEMBL29205175 | 0.80 | MGLL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |