SCHEMBL29206337

SCHEMBL29206337

Fc1cccc(C(F)c2ncccn2)c1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
BCHE P06276 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
P4HB P07237 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
RXRA P19793 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
HDAC4 P56524 1/20 0.31
REV1 Q9UBZ9 1/20 0.30
GLS O94925 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29100191 0.77 CES2 (0.44) CES2CES1BCHELMNAMAPT
SCHEMBL5739585 0.74 HDAC4 (0.34) CES2CES1MAPTHDAC4
SCHEMBL16956757 0.72 CES2 (0.47) CES2CES1BCHEGLS
SCHEMBL7465151 0.71 KCNH2 (0.34) CES2CES1GLS
SCHEMBL6405941 0.69 CES2 (0.44) CES2CES1BCHEGLS
SCHEMBL7777116 0.69 CES2 (0.53) CES2CES1BCHELMNAMAPT
SCHEMBL27994894 0.69 CES2 (0.48) CES2CES1BCHEMAPTGLS
SCHEMBL6824093 0.69 CES2 (0.44) CES2CES1BCHEREV1GLS
SCHEMBL1600457 0.69 CES2 (0.44) CES2CES1BCHEHDAC4GLS
SCHEMBL28775062 0.67 ADRA2A (0.45) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409690-A Novel insect repellent compound 拜耳动物保健有限责任公司 2025-02-11 CN disclosed
CN-114981276-B Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2024-09-27 CN disclosed
CN-117956984-A Novel microparticles containing active substances 巴斯夫欧洲公司 2024-04-30 CN disclosed