SCHEMBL29208302

SCHEMBL29208302

O=C1C(Cl)CCN(c2ccc(I)cc2)C1Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.35
FAAH O00519 1/20 0.35
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29208265 0.83 HRH3 (0.42) MGLLFAAH
SCHEMBL17274451 0.67 ALDH1A1 (0.37) MGLLFAAHAKR1C3
SCHEMBL1010938 0.62 LTA4H (0.33) MGLLFAAHAKR1C3
SCHEMBL13178304 0.60 HRH3 (0.61)
SCHEMBL578597 0.60 HTR2A (0.34)
SCHEMBL25306664 0.60 SMN1; SMN2 (0.44)
SCHEMBL28414579 0.59
SCHEMBL13178476 0.59 HRH3 (0.48)
SCHEMBL14345952 0.58 AKR1C3 (0.57) MGLLFAAHAKR1C3
SCHEMBL16144142 0.57 LTA4H (0.46) MGLLFAAHAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720456-A New method for synthesizing apixaban intermediate 3, 3-dichloro-1- (4-substituted phenyl) piperidine-2-ketone 华东理工大学 2024-03-19 CN disclosed