Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345952 | 0.81 | AKR1C3 (0.57) | LTA4HL3MBTL1AKR1C3USP2FAAH | |
| SCHEMBL8338229 | 0.81 | LTA4H (0.44) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL18815076 | 0.77 | LTA4H (0.52) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL625677 | 0.77 | ALDH1A1 (0.54) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL24003567 | 0.76 | USP2 (0.53) | L3MBTL1L3MBTL3USP2MBTD1TP53BP1 | |
| SCHEMBL14862764 | 0.76 | LTA4H (0.45) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL22837853 | 0.76 | LTA4H (0.41) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL22837830 | 0.76 | HTR2A (0.43) | LTA4HL3MBTL1L3MBTL3AKR1C3USP2 | |
| SCHEMBL17522147 | 0.76 | MAPT (0.53) | LTA4HL3MBTL1AKR1C3USP2FAAH | |
| SCHEMBL4434108 | 0.75 | LTA4H (0.56) | LTA4HL3MBTL1L3MBTL3AKR1C3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414352-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-10-01 | — | — | EP | disclosed |