Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GFER | P55789 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815076 | 0.89 | LTA4H (0.52) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL625677 | 0.89 | ALDH1A1 (0.54) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL15268156 | 0.88 | ADRB1 (0.57) | AKR1C3LTA4HALDH1A1MAPTHTT | |
| SCHEMBL1433274 | 0.88 | MAPT (0.63) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL10320300 | 0.87 | ALDH1A1 (0.58) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL133561 | 0.87 | ALDH1A1 (0.58) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL1432961 | 0.85 | AKR1C3 (0.65) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL11326562 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EGFERADRA2C | |
| SCHEMBL17522147 | 0.83 | MAPT (0.53) | AKR1C3LTA4HALDH1A1MAPTKDM4E | |
| SCHEMBL7513534 | 0.83 | LTA4H (0.47) | AKR1C3LTA4HALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146261-A2 | BIOMOLECULE-LINKED BIOMIMETIC SCAFFOLDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-21 | — | — | WO | disclosed |